Research

Our lab uses a variety of approaches to explore different aspects of biology. These draw upon various disciplines such as cell biology, biochemistry, pharmacology, medicinal and organic chemistry as illustrated by the projects below.

Carfilzomib/KyprolisTM

The next generation proteasome inhibitor

Chemical Biology

Exploring cell biology using small molecules

Regenerative Biology

Studying nature’s induced Pluripotent Stem Cells (iPSCs)

The Undruggable Proteome

Controlling intracellular protein levels using small molecules