Publications
| 104. |
A HaloTag-based Small Molecule Microarray Screening Methodology with Increased Sensitivity and Multiplex Capabilities Noblin DJ, Page CM, Tae HS, Gareiss PC, Schneekloth JS, Crews CMACS Chemical Biology 2012 (): |
| 103. |
Small-Molecule Inhibitors of the Interaction between the E3 Ligase VHL and HIF1α Buckley DL, Gustafson JL, Van Molle I, Roth AG, Tae HS, Gareiss PC, Jorgensen WL, Ciulli A, Crews CMAngew. Chem. Int. 2012 doi: 10.1002/anie.201206231(): |
| 102. |
Dissecting Fragment-Based Lead Discovery at the von Hippel-Lindau protein:Hypoxia Inducible Factor 1α Protein-Protein Interface Van Molle I, Thomann A, Buckley DL, So EC, Lang S, Crews CM, Ciulli AChemistry & Biology 2012 19():1300-1312 |
| 101. |
Greasy tags for protein removal. Neklesa TK, Crews CMNature 2012 487(19):308-309 |
| 100. |
Targeting the von Hippel-Lindau E3 Ubiquitin Ligase using Small Molecules to Disrupt the VHL-HIF-1alpha Interaction. Buckley DL, Van Molle I, Gareiss PC, Tae H-S, Miche J, Noblin DJ, Jorgensen WL, Ciulli A, Crews CMJ. Am. Chem. Soc 2012 134(10):4465-4468 |
| 99. |
Microarray Analysis of microRNA Expression during Axolotl Limb Regeneration Holman EC, Campbell LJ, Hines J, Crews CMPLOS|One 2012 7(9):1-10 |
| 98. |
Identification of Hydrophobic Tags for Degradation of Stabilized Proteins. Tae H-S, Sundberg TB, Neklesa TK, Noblin DJ, Gustafson JL, Roth AG, Raina K, Crews CMChemBioChem 2012 13(4):538-541 |
| 97. |
Gene expression profile of the regeneration epithelium during axolotl limb regeneration. Campbell LJ, Suárez-Castillo EC, Ortiz-Zuazaga H, Knapp D, Tanaka EM, Crews CMDev Dyn 2011 240(7):1826-1840 |
| 96. |
A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation. Fedeles SV, Tian X, Gallagher AR, Mitobe M, Nishio S, Lee SH, Cai Y, Geng L, Crews CM, Somlo SNat Genet 2011 43(7):639-647 |
| 95. |
Proteasome Inhibitors. Kauffman MG, Molineaux CJ, Kirk CJ, Crews CMCancer: Principles & Practice of Oncology (Eds., Devita VT, Lawrence TS, Rosenberg SA, DePinho RA) 2011 Chapter 41():441-449 |
| 94. |
Disruption of Wnt Planar Cell Polarity Signaling by Aberrant Accumulation of the MetAP-2 Substrate Rab37. Sundberg TB, Darricarrere N, Cirone P, Li X, McDonald L, Mei X, Westlake CJ, Clusarski DC, Beynon RJ, Crews CMChemistry & Biology 2011 18(10):1300-1311 |
| 93. |
Triptolide Directly Inhibits dCTP pyrophosphatase. Corson TW, Cavga H, Aberle N, Crews CMChemBioChem 2011 12(11):1767-1773 |
| 92. |
Small-molecule hydrophobic tagging-induced degradation of HaloTag Fusion proteins. Neklesa TK, Tae HS, Schneekloth AR, Stulberg MJ, Corson TW, Sundberg TB, Raina K, Holley SA, Crews CMNat Chem Biol 2011 7(8):538-43 |
| 91. |
Unexpected stereochemical tolerance for the biological activity of tyroscherin. Tae HS, Hines J, Schneekloth AR, Crews CMBioorg Med Chem 2011 19(5):1708-1713 |
| 90. |
HIV protease-mediated activation of sterically capped proteasome inhibitors and substrates. Buckley DL, Corson TW, Aberle N, Crews CMJ Am Chem Soc 2011 133(4):698-700 |
| 89. |
Natural Product Inhibitors of the Ubiquitin-Proteasome Pathway. Schneekloth JS JR., Crews CMCurr Drug Targets 2011 12(11):1581-1594 |
| 88. |
Targeted Intracellular Protein Degradation as a Potential Therapeutic Strategy. Schneekloth A, Crews CMNew Frontiers in Chemical Biology: Enabling Drug Discovery (Mark Bunnage, Editor) 2010 (): |
| 87. |
Total synthesis and biological evaluation of tyroscherin. Tae HS, Hines J, Schneekloth AR, Crews CMOrg Lett 2010 12(19):4308-4311 |
| 86. |
Targeting the Undruggable Proteome: The Small Molecules of My Dreams. Crews CMChemistry & Biology 2010 17(6):551-555 |
| 85. |
Reversal of TNP-470-Induced Endothelial Cell Growth Arrest by Guanine and Guanine Nucleosides. Hines J, Ju R, Dutschman GE, Cheng YC, Crews CMJ Pharmacol Exp Ther 2010 334(3):729-738 |