Craig Crews Biosketch

CRAIG MARTIN CREWS, Ph.D.

Lewis B. Cullman Professor of Molecular, Cellular, and Developmental Biology
Department of Chemistry
Department of Pharmacology
Yale University

Education

1987-1993    Ph.D., Biochemistry, Harvard University, with Dr. R.L. Erikson
1986-1987    DAAD Fellow, Universität Tübingen, Germany
1982-1986    B.A., Chemistry, (minor in Biology), University of Virginia

Professional Experience

2010-            Lewis B. Cullman Professor of Molecular, Cellular, and Developmental Biology
2007-            Professor, Yale University, Dept. of MCDB
2007-            Professor, Yale University, Dept. of Chemistry
2007-            Professor, Yale University, Dept. of Pharmacology
2003             Co-Founder, Proteolix, Inc. (sold to Onyx Pharmaceuticals, 2009)
2003-            Executive Director, Yale Small Molecule Discovery Center
2001-2007    Associate Professor, Yale University, Dept of Chemistry
2000-2007    Associate Professor, Yale University, Dept of MCDB (tenured 2001)
2000-2007    Associate Professor, Yale School of Medicine, Dept of Pharmacology
1998-2000    Assistant Professor, Yale School of Medicine, Dept of Pharmacology
1995-2000    Assistant Professor, Yale University, Dept of Molecular, Cellular & Developmental Biology
1993-1995    Postdoctoral Fellow, Dept. of Chemistry, Harvard University, with Dr. Stuart Schreiber

Honors and Awards                                     

2011             Senior Scholar Award, Ellison Medical Foundation
2010-2013    Visiting Professor (Gast Professor), Universität Konstanz, Germany
2010             Lewis B. Cullman Professor of Molecular, Cellular, and Developmental Biology
2006             Bessel Research Award, Alexander von Humboldt Foundation, Germany
2005-            Fellow of the Royal Society of Chemistry
1999             Arthur Greer Memorial Prize (Outstanding Junior Faculty in the Social or Natural Sciences)
1996-1998    CaPCURE Research Award (Association for the Cure of Cancer of the Prostate)
1996-1999    Donaghue Foundation New Investigator Award 
1996-1999    Burroughs Wellcome Fund New Investigator Award
1993-1995    Cancer Research Institute Postdoctoral Fellowship      
1986-1987    DAAD Research Fellowship (German Academic Exchange Service)

Editorial Boards

2010-            Editorial Board, ChemBioChem
2008-            Editor, Chemistry & Biology
2005-2009    Editorial Board, Molecular Biosystems
2001-            Editorial Board, Chemistry & Biology
2001-2009    Editorial Board, Molecular and Cellular Proteomics

Patents

‘Enzyme Inhibition’ Patent US 6,831,099 B1
‘Enzyme Inhibition’ Patent US 7,476,650
‘Proteolysis-Targeting Chimeric Pharmaceutical’ Patent US 7,041,298  
‘Proteolysis-Targeting Chimeric Pharmaceutical’ Patent US 7,208,157
‘Compounds for Enzyme Inhibition’ Patent US 7,232,818
‘Compounds for Enzyme Inhibition’ Patent US 7,491,704

FDA Approved Drugs

Carfilzomib/Kyprolis™ (based on the YU101 structure): approved for relapsed multiple myeloma (7/20/12)

Laboratory Website

crewslab.yale.edu

Complete CV